Semaglutide ODT is an orally dissolving tablet formulation of semaglutide, a GLP-1 receptor agonist. Instead of a weekly injection, you place a small tablet under your tongue where it dissolves and is absorbed.

It works by mimicking the GLP-1 hormone your body naturally produces — helping regulate appetite, reduce cravings, and support healthy blood sugar levels.

Place the tablet under your tongue and let it dissolve completely. Do not chew, crush, or swallow the tablet whole. Your provider will give you specific instructions on timing and frequency as part of your treatment plan.

• Take on an empty stomach for best absorption
• Avoid eating or drinking for at least 30 minutes after dosing
• Follow your provider’s titration schedule exactly as prescribed

The active ingredient targets the same GLP-1 pathway. The difference is the delivery method — a dissolving tablet instead of a subcutaneous injection. ODT may be preferred by patients who:

• Have needle anxiety or discomfort with self-injection
• Want a more convenient, travel-friendly dosing option
• Prefer oral medication as part of their daily routine

Your provider will help determine which format is the best clinical fit for you.

A licensed healthcare provider will review your medical history, current medications, and treatment goals during your online visit. If you meet clinical criteria, your provider may prescribe semaglutide ODT as part of your personalized plan.

Eligibility is determined on a case-by-case basis — complete your online intake to get started.

As with any GLP-1 therapy, some patients may experience side effects — particularly during the initial adjustment period. Commonly reported effects include:

• Nausea or mild stomach discomfort
• Reduced appetite
• Fatigue or lightheadedness
• Changes in bowel habits

Most side effects are temporary and decrease as your body adjusts. Your provider can modify your dosage if needed. Always message your provider through the Patient Portal with any concerns.

No. Compounded semaglutide is not reviewed or approved by the FDA for safety or effectiveness. It is prepared by licensed compounding pharmacies and prescribed by a healthcare provider when commercially manufactured products are not accessible or not preferred.

For information about FDA-approved semaglutide products, visit fda.gov.

Results vary from person to person. Some women notice changes in appetite and cravings within the first few weeks, while visible weight changes typically develop over several months of consistent use.

Your provider will monitor your progress and adjust your plan as needed. Pairing medication with healthy nutrition and movement can support better outcomes.

Switching between formulations requires provider review and approval. If you’d like to explore a different delivery method, message your care team through your Patient Portal — they’ll evaluate what’s clinically appropriate for your situation.

Your medication ships in discreet, plain packaging with no indication of its contents. Temperature-sensitive orders include insulated packaging with cold packs to maintain stability during transit.

• Shipped via UPS or FedEx with tracking
• Typically ships within 1–2 business days after provider approval
• Follow the storage instructions included with your order upon delivery

Good Girl Rx does not require or accept insurance. All pricing is transparent and all-inclusive — medication, supplies, and shipping are included in your plan.

• FSA & HSA cards are accepted for 3-month or longer plans
• Itemized receipts are provided for self-submission to your benefits provider